Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1S | P09871 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 5/20 | 0.40 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.37 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558495 | 0.79 | ABCC9 (0.46) | C1SNAMPTABCC9ABCC8KCNJ11 | |
| SCHEMBL8163851 | 0.75 | CYP11B1 (0.43) | C1SPKMKMT2AMEN1GRM4 | |
| SCHEMBL30628608 | 0.75 | PRMT1 (0.40) | — | |
| SCHEMBL29468572 | 0.73 | KMT2A (0.59) | PKMABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL822302 | 0.73 | KMT2A (0.59) | PKMABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL15531384 | 0.72 | NAMPT (0.51) | NAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL15607666 | 0.72 | KMT2A (0.57) | PKMABCC9ABCC8KCNJ11KCNJ8 | |
| Hydrochloric Acid SCHEMBL11279258 | 0.72 | KMT2A (0.57) | PKMABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL16820411 | 0.71 | HTR2A (0.55) | NAMPTABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL15530698 | 0.71 | NAMPT (0.51) | NAMPTABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849736-A | Isoxazoline and isoxazole fibrinogen receptor antagonists | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-12-15 | — | — | US | disclosed |