Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.46 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.46 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.46 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.46 |
| ▸ | C1S | P09871 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.44 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558497 | 0.83 | GAA (0.61) | F2PRSS1PRSS2PRSS3TMPRSS6 | |
| SCHEMBL9029174 | 0.82 | ALDH1A1 (0.45) | F2MRGPRX1ALDH1A1MAPTHPGD | |
| SCHEMBL8163851 | 0.80 | CYP11B1 (0.43) | C1SF2HTTALDH1A1MAPT | |
| SCHEMBL8558127 | 0.80 | F10 (0.47) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL9031533 | 0.80 | F2 (0.51) | F2PRSS1PRSS2PRSS3MRGPRX1 | |
| SCHEMBL31038387 | 0.79 | GAA (0.67) | ABCC9ABCC8KCNJ11KCNJ8HTT | |
| SCHEMBL6151129 | 0.79 | GAA (0.67) | ABCC9ABCC8KCNJ11KCNJ8HTT | |
| SCHEMBL822302 | 0.79 | KMT2A (0.59) | ABCC9ABCC8KCNJ11KCNJ8HTT | |
| SCHEMBL29468572 | 0.79 | KMT2A (0.59) | ABCC9ABCC8KCNJ11KCNJ8HTT | |
| SCHEMBL8624231 | 0.79 | C1S (0.41) | ABCC9ABCC8KCNJ11KCNJ8C1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |