SCHEMBL472573

SCHEMBL472573

CN1C(=O)CC(=O)N(C)C1=S

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 2/20 0.42
GSK3B P49841 2/20 0.42
GAA P10253 4/20 0.32
MEN1 O00255 3/20 0.32
MAPT P10636 3/20 0.32
KMT2A Q03164 3/20 0.32
PSMD14 O00487 2/20 0.32
ALDH1A1 P00352 2/20 0.32
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 1/20 0.32
MAPK1 P28482 1/20 0.32
BRD4 O60885 1/20 0.31
BRD2 P25440 1/20 0.31
MGLL Q99685 1/20 0.30
KDM4E B2RXH2 1/20 0.30
THRB P10828 1/20 0.30
RECQL P46063 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23894741 0.81 GSK3A (0.38) GSK3AGSK3BGAAMEN1MAPT
SCHEMBL7945735 0.81
SCHEMBL11862932 0.79 GSK3A (0.33) GSK3AGSK3BGAAKDM4ETHRB
SCHEMBL6374912 0.79 F2 (0.37) GSK3AGSK3BGAAMEN1MAPT
SCHEMBL11876303 0.79 GSK3A (0.38) GSK3AGSK3BGAAMEN1KMT2A
SCHEMBL11872002 0.78 MAPT (0.33) GSK3AGSK3BGAAMEN1MAPT
SCHEMBL18863391 0.77 GSK3A (0.32) GSK3AGSK3BGAABRD4BRD2
SCHEMBL145601 0.75 KMT2A (0.35) GSK3AGSK3BGAAMEN1MAPT
SCHEMBL11868886 0.75 KDM4E (0.43) GAAMEN1MAPTKMT2AALDH1A1
SCHEMBL11867011 0.75 GAA (0.41) GSK3AGSK3BGAAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250250418-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME HUNTSMAN PETROCHEMICAL LLC 2025-08-07 US claimed
EP-4508111-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME Huntsman Petrochemical LLC (US) 2025-02-19 EP claimed
WO-2023200641-A1 MIXTURE FOR INHIBITING THE EMISSION OF ALDEHYDES FROM POLYURETHANE FOAM FOR AN EXTENDED PERIOD OF TIME HUNTSMAN PETROCHEMICAL LLC (US) 2023-10-19 WO claimed
US-10844282-B2 Corrosion inhibiting formulations and uses thereof KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2020-11-24 US claimed
US-20200291297-A1 CORROSION INHIBITING FORMULATIONS AND USES THEREOF KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2020-09-17 US claimed
US-9875904-B2 Silicon etching liquid, silicon etching method, and microelectromechanical element MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-01-23 US claimed
US-20150340241-A1 SILICON ETCHING LIQUID, SILICON ETCHING METHOD, AND MICROELECTROMECHANICAL ELEMENT MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2015-11-26 US claimed
US-9194806-B2 Means for detecting oxygen free radicals in human body DFI CO., LTD. (KR) 2015-11-24 US claimed
EP-2811297-A1 MEANS FOR DETECTING OXYGEN FREE RADICALS IN HUMAN BODY DFI Co., Ltd. (KR) 2014-12-10 EP claimed
US-20140302613-A1 MEANS FOR DETECTING OXYGEN FREE RADICALS IN HUMAN BODY DFI Co.,Ltd. (KR) 2014-10-09 US claimed
US-20050060817-A1 Use of ninhydrin derivatives bearing an unsaturated system for dyeing keratin material L'OREAL S.A. (FR) 2005-03-24 US claimed
US-20050050653-A1 Process for dyeing keratin fibers with ninhydrin compounds comprising one or more fused rings L'OREAL S.A. (FR) 2005-03-10 US claimed
US-20050050654-A1 Process for dyeing keratin fibers with at least one ninhydrin derivative L'OREAL S.A. (FR) 2005-03-10 US claimed
US-20050050652-A1 Process for dyeing keratin fibers with at least one polycyclic aromatic vicinal trione L'OREAL S.A. (FR) 2005-03-10 US claimed
US-20050050651-A1 Use of at least one ninhydrin derivative for dyeing L'OREAL S.A. (FR) 2005-03-10 US claimed
US-20050050655-A1 Process for dyeing keratin fibers comprising at least one aryl or aryloxy substitutent-based ninhydrin derivative L'OREAL S.A. (FR) 2005-03-10 US claimed
US-6790239-B1 COMBINATION OF AROMATIC ALDEHYDES OR KETONES AND CH-ACTIVE COMPOUNDS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-09-14 US claimed
US-6770102-B1 AROMATIC ALDEHYDES OR KETONES AND CH-ACTIVE COMPOUNDS; DOES NOT REQUIRE OXIDIZING AGENT; BRILLIANCE; COLOR DEPTH; WIDE VARIETY OF SHADES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-08-03 US claimed
EP-1139990-B1 AGENT FOR DYING KERATIN FIBERS HENKEL KGAA (DE) 2004-05-06 EP claimed
EP-1139988-B1 AGENT FOR DYING KERATIN FIBERS HENKEL KGAA (DE) 2002-09-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050060817-A1 Use of ninhydrin derivatives bearing an unsaturated system for dyeing keratin material KRT18, NISCH, JUP GSK3A 2383/4885GSK3B 2376/4885GAA 4069/4885
US-20050050653-A1 Process for dyeing keratin fibers with ninhydrin compounds comprising one or more fused rings KRT18, NISCH, JUP GSK3A 4141/4885GSK3B 3912/4885GAA 4066/4885
US-20050050652-A1 Process for dyeing keratin fibers with at least one polycyclic aromatic vicinal trione KRT18, HKDC1, JUP GSK3A 2313/4885GSK3B 2161/4885GAA 3334/4885
US-20050050654-A1 Process for dyeing keratin fibers with at least one ninhydrin derivative KRT18, DSG1, ACR GSK3A 1426/4885GSK3B 1066/4885GAA 2995/4885
US-20050050655-A1 Process for dyeing keratin fibers comprising at least one aryl or aryloxy substitutent-based ninhydrin derivative KRT18, JUP, NISCH GSK3A 2308/4885GSK3B 1795/4885GAA 2421/4885
US-20050050651-A1 Use of at least one ninhydrin derivative for dyeing NISCH, NPM1, NCDN GSK3A 1879/4885GSK3B 1568/4885GAA 2271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.