Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11177588 | 0.91 | PTGS2 (0.81) | PTGS2PTGS1 | |
| Flosulide SCHEMBL195509 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1 | |
| Flosulide SCHEMBL29454969 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1 | |
| Flosulide SCHEMBL29383035 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL11182826 | 0.83 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL14280458 | 0.82 | PTGS2 (0.82) | PTGS2PTGS1 | |
| SCHEMBL18214537 | 0.81 | PTGS2 (0.78) | PTGS2PTGS1 | |
| SCHEMBL8623711 | 0.80 | PTGS2 (0.75) | PTGS2PTGS1 | |
| SCHEMBL11181115 | 0.78 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL3247329 | 0.76 | PTGS2 (0.66) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811416-A | ADMINISTERING TO TREAT DISORDERS SUCH AS DYSMENORRHEA, PRETERM LABOR, PREECLAMPSIA, OR FETAL GROWTH RETARDATION; ALSO HORMONE REPLACEMENT THERAPY, HYPERTENSION | BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM (US) | 1998-09-22 | — | — | US | disclosed |
| EP-0844884-A2 | ENDOTHELIN ANTAGONISTS AND ENDOTHELIN SYNTHASE INHIBITORS FOR THE PREVENTION AND TREATMENT OF UTERINE CONTRACTILITY DISORDERS, PREECLAMPSIA, ATHEROSCLEROTIC VASCULAR DISEASE, HYPERTENSION AND FOR HORMONE REPLACEMENT THERAPY | CHWALISZ, Krzysztof (DE) | 1998-06-03 | — | — | EP | disclosed |
| WO-1996035453-A2 | ENDOTHELIN ANTAGONISTS AND ENDOTHELIN SYNTHASE INHIBITORS FOR THE PREVENTION AND TREATMENT OF INTERINE CONTRACTILITY DISORDERS, PREECLAMPSIA, ATHEROSCLEROTIC VASCULAR DISEASE, HYPERTENSION AND OR HORMONE REPLACEMENT THERAPY | CHWALISZ KRISTOF (DE) | 1996-11-14 | — | — | WO | disclosed |