Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8286625 | 0.75 | CA12 (0.57) | CA12CA1CA2CA9GSK3B | |
| SCHEMBL8626807 | 0.72 | CA12 (0.34) | CA12CA1CA2CA9GSK3B | |
| SCHEMBL8761369 | 0.70 | MEN1 (0.34) | CA12CA1CA2CA9GRIA2 | |
| SCHEMBL8761319 | 0.68 | ALDH1A1 (0.39) | CA12CA1CA2CA9GRIA2 | |
| SCHEMBL393138 | 0.66 | ALDH1A1 (0.39) | — | |
| SCHEMBL8815527 | 0.66 | ALDH1A1 (0.42) | — | |
| SCHEMBL4264221 | 0.65 | ABCC8 (0.45) | GRIA1GRIA2 | |
| SCHEMBL393125 | 0.65 | ALDH1A1 (0.41) | — | |
| SCHEMBL8626193 | 0.65 | KDM4E (0.40) | GSK3BGRIA2 | |
| SCHEMBL393126 | 0.64 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618209-B1 | Pyridothiadiazines, processes for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1998-12-23 | — | — | EP | disclosed |
| US-5459138-A | Dysfunctions of glutamatergic neurotransmission associated with learning and memory | ADIR ET COMPAGNIE (FR) | 1995-10-17 | — | — | US | disclosed |
| EP-0618209-A1 | Pyridothiadiazines, processes for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-10-05 | — | — | EP | disclosed |