Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46341 | 0.77 | ALDH1A1 (0.35) | LMNAHPGDALDH1A1HSD17B10HTT | |
| SCHEMBL7328412 | 0.76 | HSD17B10 (0.53) | LMNAHPGDALDH1A1HSD17B10HTT | |
| SCHEMBL21377510 | 0.76 | HSD17B10 (0.53) | LMNAHPGDALDH1A1HSD17B10HTT | |
| SCHEMBL19023154 | 0.76 | HPGD (0.37) | LMNAHPGDALDH1A1HSD17B10HTT | |
| SCHEMBL8473870 | 0.76 | HSD17B10 (0.34) | LMNAHPGDALDH1A1HSD17B10HTT | |
| SCHEMBL17432908 | 0.76 | HSD17B10 (0.34) | LMNAHPGDALDH1A1HSD17B10HTT | |
| SCHEMBL8624806 | 0.75 | HSD17B10 (0.35) | LMNAHPGDALDH1A1HSD17B10HTT | |
| SCHEMBL8625594 | 0.74 | PDE10A (0.32) | KDM1AKCNJ1 | |
| SCHEMBL8628216 | 0.73 | PDE10A (0.35) | LMNAHPGDALDH1A1HSD17B10HTT | |
| SCHEMBL8627277 | 0.73 | KCNJ1 (0.38) | HPGDALDH1A1HSD17B10CYP11B2KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767128-A | ANALGESICS | ADIR ET COMPAGNIE (FR) | 1998-06-16 | — | — | US | disclosed |
| US-5618819-A | ANALGESICS | ADIR ET COMPAGNIE (FR) | 1997-04-08 | — | — | US | disclosed |
| EP-0691339-A1 | Amine derivatives of 1,3-dihydro-2H-pyrrolo(2,3-b)pyridin-2-ones and oxazolo(4,5-b)pyridin-2(3H)-ones, their process of preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-01-10 | — | — | EP | disclosed |