Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8630456 | 0.92 | PDE10A (0.36) | PDE10AALDH1A1KDM4EKCNJ1HPGD | |
| SCHEMBL8624806 | 0.82 | HSD17B10 (0.35) | PDE10AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7326070 | 0.81 | ALDH1A1 (0.35) | PDE10AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8918622 | 0.81 | HRH3 (0.41) | TDP1L3MBTL1SYK | |
| SCHEMBL8921432 | 0.78 | HTR1A (0.34) | PDE10AALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL8625812 | 0.77 | SIGMAR1 (0.42) | PDE10AALDH1A1RXFP1HPGDPKM | |
| SCHEMBL8625594 | 0.77 | PDE10A (0.32) | PDE10AKCNJ1 | |
| SCHEMBL8917996 | 0.77 | SIGMAR1 (0.44) | ALDH1A1KMT2AHPGDSRCPOLB | |
| SCHEMBL19023154 | 0.76 | HPGD (0.37) | ALDH1A1KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL46341 | 0.74 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2ATDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767128-A | ANALGESICS | ADIR ET COMPAGNIE (FR) | 1998-06-16 | — | — | US | disclosed |
| US-5618819-A | ANALGESICS | ADIR ET COMPAGNIE (FR) | 1997-04-08 | — | — | US | disclosed |
| EP-0691339-A1 | Amine derivatives of 1,3-dihydro-2H-pyrrolo(2,3-b)pyridin-2-ones and oxazolo(4,5-b)pyridin-2(3H)-ones, their process of preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-01-10 | — | — | EP | disclosed |