Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271545 | 0.81 | — | — | |
| SCHEMBL10297565 | 0.81 | — | — | |
| SCHEMBL10297566 | 0.81 | — | — | |
| SCHEMBL28201185 | 0.77 | LMNA (0.41) | TSHRLMNA | |
| SCHEMBL7049114 | 0.77 | TSHR (0.36) | TSHRLMNA | |
| SCHEMBL28138198 | 0.77 | TSHR (0.36) | TSHRLMNA | |
| SCHEMBL9163393 | 0.76 | TSHR (0.35) | TSHRLMNACHRM1AKR1A1CHRM3 | |
| SCHEMBL3818495 | 0.76 | TSHR (0.39) | TSHRLMNACHRM1AKR1A1CHRM3 | |
| SCHEMBL21462142 | 0.76 | TSHR (0.39) | TSHRLMNACHRM1AKR1A1CHRM3 | |
| SCHEMBL16074672 | 0.75 | TSHR (0.36) | TSHRLMNACHRM1AKR1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998055085-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS | CODON PHARMACEUTICALS, INC. (US) | 1998-12-10 | — | — | WO | disclosed |