Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.57 |
| ▸ | HRAS | P01112 | 1/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10776729 | 0.86 | HRAS (0.68) | HRASNPC1RAB9AGAABCHE | |
| SCHEMBL206646 | 0.84 | HRAS (0.65) | HRASNPC1RAB9ABCHETSHR | |
| Hydrochloric Acid SCHEMBL6967279 | 0.82 | HRAS (0.62) | HRASNPC1RAB9AGAABCHE | |
| SCHEMBL7062567 | 0.78 | MAOB (0.69) | MAOBLOXL2SMN1; SMN2NPC1RAB9A | |
| Methyl Alcohol SCHEMBL27462113 | 0.78 | HRAS (0.64) | HRASSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL8897410 | 0.78 | LOXL2 (0.61) | MAOBLOXL2MAOAKDM1ABCHE | |
| SCHEMBL10802765 | 0.77 | HRAS (0.58) | HRASSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL13793595 | 0.77 | CYP2A6 (0.53) | MAOBLOXL2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8339266 | 0.77 | HRAS (0.54) | HRASNPC1RAB9ABCHETSHR | |
| SCHEMBL27762312 | 0.75 | MAOB (0.56) | MAOBLOXL2SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0689549-B1 | NEW UREA DERIVATES, THEIR PREPARATION AND THEIR USE | HOECHST AG (DE) | 1998-06-17 | — | — | EP | disclosed |
| US-5703050-A | INHIBIT PLATELET AGGREGATION, METASTASIS OF CARCINOMA CELLS, OSTEOCLAST BINDING TO BONE SURFACE | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-30 | — | — | US | disclosed |
| EP-0689549-A1 | NEW UREA DERIVATES, THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-03 | — | — | EP | disclosed |
| WO-1994022907-A1 | NEW UREA DERIVATES, THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | disclosed |