Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 8/20 | 0.54 |
| ▸ | FNTB | P49356 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8626201 | 0.90 | FNTA (0.48) | FNTAFNTBMAPTKMT2AMEN1 | |
| SCHEMBL8626764 | 0.89 | FNTA (0.60) | FNTAFNTBMAPTALDH1A1 | |
| SCHEMBL8623763 | 0.83 | FNTA (0.57) | FNTAFNTBKMT2AMEN1ALDH1A1 | |
| SCHEMBL9828951 | 0.81 | FNTA (0.62) | FNTAFNTBKMT2AMEN1ALDH1A1 | |
| SCHEMBL2324069 | 0.81 | FNTA (0.62) | FNTAFNTBKMT2AMEN1ALDH1A1 | |
| SCHEMBL8623835 | 0.81 | FNTA (0.52) | FNTAFNTBMAPTALDH1A1CA2 | |
| SCHEMBL8624885 | 0.80 | FNTA (0.52) | FNTAFNTBALDH1A1USP2TSHR | |
| SCHEMBL6384342 | 0.80 | FNTA (0.59) | FNTAFNTBMAPTALDH1A1 | |
| SCHEMBL2330739 | 0.79 | FNTA (0.53) | FNTAFNTBALDH1A1USP2TSHR | |
| SCHEMBL2330735 | 0.79 | FNTA (0.53) | FNTAFNTBALDH1A1USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842150-A1 | NOVEL FARNESYL TRANSFERASE INHIBITORS, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID INHIBITORS | Aventis Pharma S.A. (FR) | 1998-05-20 | — | — | EP | disclosed |
| EP-0764149-A1 | NOVEL FARNESYL TRANSFERASE INHIBITORS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1997-03-26 | — | — | EP | disclosed |
| WO-1997003047-A1 | NOVEL FARNESYL TRANSFERASE INHIBITORS, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID INHIBITORS | Rhône-Poulenc Rorer S.A. (FR) | 1997-01-30 | — | — | WO | disclosed |
| WO-1995034535-A1 | NOVEL FARNESYL TRANSFERASE INHIBITORS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1995-12-21 | — | — | WO | disclosed |