Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 9/20 | 0.60 |
| ▸ | FNTB | P49356 | 9/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623835 | 0.90 | FNTA (0.52) | FNTAFNTBALDH1A1MAPT | |
| SCHEMBL8624850 | 0.89 | FNTA (0.54) | FNTAFNTBALDH1A1MAPT | |
| SCHEMBL8623007 | 0.83 | FNTA (0.67) | FNTAFNTBALDH1A1 | |
| SCHEMBL2324069 | 0.82 | FNTA (0.62) | FNTAFNTBALDH1A1 | |
| SCHEMBL9828951 | 0.82 | FNTA (0.62) | FNTAFNTBALDH1A1 | |
| SCHEMBL8371075 | 0.81 | FNTA (0.57) | FNTAFNTBALDH1A1 | |
| SCHEMBL8626201 | 0.81 | FNTA (0.48) | FNTAFNTBMAPT | |
| SCHEMBL26885154 | 0.79 | LMNA (0.56) | MAPT | |
| SCHEMBL6384342 | 0.79 | FNTA (0.59) | FNTAFNTBALDH1A1MAPT | |
| SCHEMBL2330735 | 0.78 | FNTA (0.53) | FNTAFNTBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842150-A1 | NOVEL FARNESYL TRANSFERASE INHIBITORS, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID INHIBITORS | Aventis Pharma S.A. (FR) | 1998-05-20 | — | — | EP | disclosed |
| EP-0764149-A1 | NOVEL FARNESYL TRANSFERASE INHIBITORS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1997-03-26 | — | — | EP | disclosed |
| WO-1997003047-A1 | NOVEL FARNESYL TRANSFERASE INHIBITORS, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID INHIBITORS | Rhône-Poulenc Rorer S.A. (FR) | 1997-01-30 | — | — | WO | disclosed |
| WO-1995034535-A1 | NOVEL FARNESYL TRANSFERASE INHIBITORS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1995-12-21 | — | — | WO | disclosed |