Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 6/20 | 0.48 |
| ▸ | FNTB | P49356 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624850 | 0.90 | FNTA (0.54) | FNTAFNTBKMT2AMAPTMEN1 | |
| SCHEMBL8623835 | 0.89 | FNTA (0.52) | FNTAFNTBMAPTCA1CA2 | |
| SCHEMBL8621284 | 0.83 | FNTA (0.52) | FNTAFNTBKMT2AMEN1CA1 | |
| SCHEMBL8626764 | 0.81 | FNTA (0.60) | FNTAFNTBMAPT | |
| SCHEMBL8619496 | 0.81 | FNTA (0.54) | FNTAFNTBCA1CA2 | |
| SCHEMBL8626003 | 0.76 | FNTA (0.56) | FNTAFNTBCA1CA2 | |
| SCHEMBL8623996 | 0.76 | FNTA (0.60) | FNTAFNTBCA1CA2 | |
| SCHEMBL8623763 | 0.72 | FNTA (0.57) | FNTAFNTBKMT2AMEN1CA1 | |
| SCHEMBL9828951 | 0.72 | FNTA (0.62) | FNTAFNTBKMT2AMEN1CA1 | |
| SCHEMBL2324069 | 0.72 | FNTA (0.62) | FNTAFNTBKMT2AMEN1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842150-A1 | NOVEL FARNESYL TRANSFERASE INHIBITORS, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID INHIBITORS | Aventis Pharma S.A. (FR) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997003047-A1 | NOVEL FARNESYL TRANSFERASE INHIBITORS, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID INHIBITORS | Rhône-Poulenc Rorer S.A. (FR) | 1997-01-30 | — | — | WO | disclosed |