Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | OGG1 | O15527 | 1/20 | 0.37 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624943 | 1.00 | GAA (0.47) | GAAALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL8602035 | 0.90 | KDM4E (0.49) | GAAALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL8626537 | 0.84 | ALDH1A1 (0.47) | GAAALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL8626276 | 0.82 | ALDH1A1 (0.51) | GAAALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL8604312 | 0.82 | ALDH1A1 (0.51) | GAAALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL8623924 | 0.82 | GAA (0.51) | GAAALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL8625020 | 0.82 | GAA (0.51) | GAAALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL11363464 | 0.80 | TBXA2R (0.65) | GAATBXA2RTBXAS1POLBLMNA | |
| SCHEMBL11363915 | 0.80 | TBXA2R (0.65) | GAATBXA2RTBXAS1POLBLMNA | |
| SCHEMBL8623814 | 0.78 | GAA (0.55) | GAAALDH1A1KDM4EHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | claimed |
| CN-1111612-A | Naphthyloxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1995-11-15 | — | — | CN | claimed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | claimed |
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5624959-A | INHIBITING UTERINE CONTRACTIONS, PROSTAGLANDIN ANTAGONIST OR AGONIST, ANALGESICS AND ANTISECRETORY AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |