Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TYMS | P04818 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | OGG1 | O15527 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604312 | 1.00 | ALDH1A1 (0.51) | ALDH1A1KDM4ETDP1HPGDKMT2A | |
| SCHEMBL8602035 | 0.83 | KDM4E (0.49) | ALDH1A1KDM4ETDP1HPGDKMT2A | |
| SCHEMBL8600099 | 0.83 | ALDH1A1 (0.51) | ALDH1A1KDM4ETDP1HPGDKMT2A | |
| SCHEMBL8624943 | 0.82 | GAA (0.47) | ALDH1A1KDM4ETDP1HPGDKMT2A | |
| SCHEMBL8624947 | 0.82 | GAA (0.47) | ALDH1A1KDM4ETDP1HPGDKMT2A | |
| SCHEMBL8600090 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4ETDP1HPGDKMT2A | |
| SCHEMBL8626804 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4ETDP1HPGDKMT2A | |
| SCHEMBL8624758 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1HPGDKMT2A | |
| SCHEMBL8604536 | 0.74 | MAPT (0.55) | ALDH1A1KDM4ETDP1HPGDKMT2A | |
| SCHEMBL8604212 | 0.74 | GAA (0.47) | ALDH1A1KDM4ETDP1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | claimed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | claimed |
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5624959-A | INHIBITING UTERINE CONTRACTIONS, PROSTAGLANDIN ANTAGONIST OR AGONIST, ANALGESICS AND ANTISECRETORY AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |