Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GALK1 | P51570 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528187 | 0.81 | MAPT (0.62) | MAPTKDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL6734945 | 0.81 | MAPT (0.62) | MAPTKDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL7539272 | 0.79 | HTT (0.54) | HTTKDM4EALDH1A1HPGDTSHR | |
| Potassium Ion SCHEMBL11635044 | 0.79 | MAPT (0.39) | HTTMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL7541780 | 0.77 | HTT (0.51) | HTTMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL9848860 | 0.74 | HTT (0.57) | HTTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL14279606 | 0.73 | KCNA5 (0.49) | HTTMAPTALDH1A1LMNAHPGD | |
| SCHEMBL4856909 | 0.73 | KCNA5 (0.49) | HTTMAPTALDH1A1LMNAHPGD | |
| SCHEMBL11720041 | 0.72 | MAPT (0.48) | HTTMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL11720022 | 0.72 | MAPT (0.48) | HTTMAPTKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547646-B1 | Crystalline form of a cephalosporin antibiotic | OPOS BIOCHIMICA SRL (IT) | 1998-06-03 | — | — | EP | disclosed |
| US-5693790-A | FORMED BY TREATING CEFACLOR WITH MINERAL OR ORGANIC ACID IN MIXTURE OF WATER AND ALCOHOL | BIOCHIMICA OPOS SPA (IT) | 1997-12-02 | — | — | US | disclosed |
| US-5589593-A | CRYSTALLIZATION OF CEFACLOR AND FORMATION OF THE HYDRATE, STABILITY | BIOCHIMICA OPOS SPA (IT) | 1996-12-31 | — | — | US | disclosed |
| EP-0547646-A2 | Crystalline form of a cephalosporin antibiotic | BIOCHIMICA OPOS SPA (IT) | 1993-06-23 | — | — | EP | disclosed |