Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 4/20 | 0.66 |
| ▸ | TLR4 | O00206 | 3/20 | 0.58 |
| ▸ | TLR2 | O60603 | 3/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ABL2 | P42684 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625069 | 1.00 | FBP1 (0.66) | FBP1TLR4TLR2ABL1EGFR | |
| SCHEMBL9181907 | 0.90 | FBP1 (0.53) | FBP1TLR4TLR2ABL1EGFR | |
| SCHEMBL9181908 | 0.90 | FBP1 (0.53) | FBP1TLR4TLR2ABL1EGFR | |
| SCHEMBL7104674 | 0.85 | FBP1 (0.60) | FBP1ABL1EGFRABL2LMNA | |
| SCHEMBL7104672 | 0.85 | FBP1 (0.60) | FBP1ABL1EGFRABL2LMNA | |
| SCHEMBL2748715 | 0.82 | MAOB (0.63) | FBP1TLR4TLR2ALDH1A1MEN1 | |
| SCHEMBL2748717 | 0.82 | MAOB (0.63) | FBP1TLR4TLR2ALDH1A1MEN1 | |
| SCHEMBL2748716 | 0.82 | MAOB (0.63) | FBP1TLR4TLR2ALDH1A1MEN1 | |
| SCHEMBL1749791 | 0.81 | FBP1 (1.00) | FBP1ABL1EGFRABL2LMNA | |
| SCHEMBL1032131 | 0.81 | FBP1 (1.00) | FBP1ABL1EGFRABL2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672646-B1 | Process for producing beta-nitro-enamines and intermediates thereof | SUMITOMO CHEMICAL CO (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5639895-A | Process for producing β-nitroenamine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-17 | — | — | US | disclosed |
| US-5597940-A | REACTING NITROOLEFIN WITH HYDROXYLAMINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0672646-A1 | Process for producing beta-nitro-enamines and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-09-20 | — | — | EP | disclosed |