Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.53 |
| ▸ | TLR4 | O00206 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ABL2 | P42684 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9181907 | 1.00 | FBP1 (0.53) | FBP1TLR4TLR2ABL1EGFR | |
| SCHEMBL8625071 | 0.90 | FBP1 (0.66) | FBP1TLR4TLR2ABL1EGFR | |
| SCHEMBL8625069 | 0.90 | FBP1 (0.66) | FBP1TLR4TLR2ABL1EGFR | |
| SCHEMBL7104674 | 0.81 | FBP1 (0.60) | FBP1ABL1EGFRABL2CYP1A2 | |
| SCHEMBL7104672 | 0.81 | FBP1 (0.60) | FBP1ABL1EGFRABL2CYP1A2 | |
| SCHEMBL14230254 | 0.79 | FBP1 (0.66) | FBP1ABL1EGFRABL2TDP1 | |
| SCHEMBL10772748 | 0.79 | FBP1 (0.65) | FBP1TLR4TLR2ABL1EGFR | |
| SCHEMBL11546305 | 0.77 | FBP1 (0.54) | FBP1ABL1EGFRABL2HTT | |
| SCHEMBL2748049 | 0.76 | FBP1 (0.66) | FBP1ABL1EGFRABL2CYP1A2 | |
| SCHEMBL2748046 | 0.76 | FBP1 (0.66) | FBP1ABL1EGFRABL2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0381291-B1 | Oximino ether compounds | SHELL INT RESEARCH (NL) | 1995-08-23 | — | — | EP | disclosed |
| EP-0381291-A1 | Oximino ether compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1990-08-08 | — | — | EP | disclosed |