Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.57 |
| ▸ | F2 | P00734 | 10/20 | 0.57 |
| ▸ | PROC | P04070 | 3/20 | 0.35 |
| ▸ | PLG | P00747 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624162 | 0.87 | F10 (0.54) | F10F2CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL8625901 | 0.79 | F10 (0.52) | F10F2CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL7425048 | 0.77 | F10 (0.75) | F10F2PROCPLGPRSS1 | |
| SCHEMBL8425417 | 0.70 | ALDH1A1 (0.35) | F10F2PROCPLGPRSS1 | |
| SCHEMBL7424077 | 0.68 | KDM4E (0.35) | F10F2PROCPLGPRSS1 | |
| SCHEMBL7423151 | 0.68 | KDM4E (0.35) | F10F2PROCPLGPRSS1 | |
| Trifluoroacetic Acid SCHEMBL7474479 | 0.68 | F10 (0.89) | F10F2PROCPLGPRSS1 | |
| Trifluoroacetic Acid SCHEMBL7474477 | 0.68 | F10 (0.89) | F10F2PROCPLGPRSS1 | |
| Hydrochloric Acid SCHEMBL8040100 | 0.68 | KDM4E (0.35) | F10F2PROCPLGPRSS1 | |
| Hydrochloric Acid SCHEMBL7423721 | 0.68 | KDM4E (0.35) | F10F2PROCPLGPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731315-A | Substituted sulfonic acid n- (aminoiminomethyl)phenylalkyl!-azaheterocyclamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-03-24 | — | — | US | disclosed |