Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.52 |
| ▸ | F2 | P00734 | 4/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624162 | 0.93 | F10 (0.54) | F10F2ROCK2ROCK1KCNH2 | |
| SCHEMBL8629049 | 0.83 | ROCK2 (0.39) | F10ROCK2ROCK1KCNH2ALDH1A1 | |
| SCHEMBL8628686 | 0.81 | KCNH2 (0.40) | F10F2ROCK2ROCK1KCNH2 | |
| SCHEMBL8625102 | 0.79 | F10 (0.57) | F10F2KCNH2FNTAFNTB | |
| SCHEMBL8625062 | 0.73 | F10 (0.59) | F10F2KCNH2CYP3A4FNTA | |
| SCHEMBL2328567 | 0.72 | F10 (0.70) | F10F2ROCK2ROCK1 | |
| SCHEMBL2335132 | 0.72 | F10 (0.53) | F10F2ROCK2ROCK1KCNH2 | |
| SCHEMBL2330834 | 0.72 | F10 (0.73) | F10F2 | |
| SCHEMBL2328605 | 0.70 | F10 (0.47) | F10F2ROCK2ROCK1KCNH2 | |
| SCHEMBL7417103 | 0.69 | FNTA (0.57) | F10ROCK2ROCK1KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731315-A | Substituted sulfonic acid n- (aminoiminomethyl)phenylalkyl!-azaheterocyclamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-03-24 | — | — | US | disclosed |