Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.43 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15464979 | 0.78 | GPR119 (0.58) | GPR119 | |
| SCHEMBL21001917 | 0.77 | KDM4E (0.56) | GPR119KDM4EMEN1KMT2A | |
| SCHEMBL29911259 | 0.77 | KDM4E (0.56) | GPR119KDM4EMEN1KMT2A | |
| SCHEMBL27802242 | 0.76 | GPR119 (0.45) | GPR119HCAR1KDM4EMAPTTHRB | |
| SCHEMBL8740247 | 0.74 | KDM4E (0.53) | GPR119KDM4EMAPTTHRBMEN1 | |
| SCHEMBL8612246 | 0.73 | FAAH (0.45) | GPR119KDM4EMAPTTHRB | |
| SCHEMBL948519 | 0.72 | CHRM2 (0.48) | GPR119MEN1KMT2A | |
| SCHEMBL21039940 | 0.72 | HPGD (0.49) | GPR119KDM4EMAPTTHRBMEN1 | |
| SCHEMBL21001915 | 0.72 | HPGD (0.49) | GPR119KDM4EMAPTTHRBMEN1 | |
| SCHEMBL2665990 | 0.72 | GPR119 (0.60) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817677-A | ANTITHROMBOSIS AGENTS | DR. KARL THOMAE GMBH (DE) | 1998-10-06 | — | — | US | disclosed |