SCHEMBL862515

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12152585	0.91	NFE2L2 (0.82)	NFE2L2PTGS1PTGS2CYP1A1CYP1A2
	SCHEMBL13535962	0.89	NFE2L2 (0.56)	NFE2L2PTGS1PTGS2CYP1A1CYP1A2
	SCHEMBL25686111	0.89	NFE2L2 (0.56)	NFE2L2PTGS1PTGS2CYP1A1CYP1A2
	SCHEMBL22049908	0.88	NFE2L2 (0.83)	NFE2L2PTGS1PTGS2HTR2AHTR2C
	SCHEMBL12152586	0.86	NFE2L2 (0.64)	NFE2L2PTGS1PTGS2CYP1A1CYP1A2
	SCHEMBL22418030	0.83	NFE2L2 (0.51)	NFE2L2PTGS1PTGS2CYP1A1CYP1A2
	SCHEMBL13348211	0.83	NFE2L2 (0.51)	NFE2L2PTGS1PTGS2CYP1A1CYP1A2
	SCHEMBL21872499	0.83	NFE2L2 (0.50)	NFE2L2PTGS1PTGS2CYP1A2NQO2
	SCHEMBL3318679	0.83	NFE2L2 (0.50)	NFE2L2PTGS1PTGS2CYP1A2NQO2
	SCHEMBL28274617	0.83	NFE2L2 (0.50)	NFE2L2PTGS1PTGS2CYP1A2NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.