Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621948 | 0.67 | CYP1A2 (0.42) | L3MBTL1CYP1A2CYP3A4HRH3SIGMAR1 | |
| SCHEMBL7455224 | 0.64 | ALOX15 (0.55) | L3MBTL1CYP1A2CYP3A4HRH3SIGMAR1 | |
| SCHEMBL7312043 | 0.64 | L3MBTL1 (0.51) | L3MBTL1CYP1A2CYP3A4HRH3SIGMAR1 | |
| SCHEMBL2643824 | 0.62 | HRH3 (0.38) | L3MBTL1CYP1A2CYP3A4HRH3SIGMAR1 | |
| SCHEMBL1854770 | 0.61 | CYP1A2 (0.43) | L3MBTL1CYP1A2CYP3A4HRH3SIGMAR1 | |
| SCHEMBL28805353 | 0.61 | HRH3 (0.37) | L3MBTL1CYP1A2CYP3A4HRH3SIGMAR1 | |
| SCHEMBL4247408 | 0.61 | CYP1A2 (0.43) | L3MBTL1CYP1A2CYP3A4HRH3SIGMAR1 | |
| SCHEMBL23828671 | 0.60 | HRH3 (0.69) | L3MBTL1CYP1A2HRH3SIGMAR1MEN1 | |
| SCHEMBL5466977 | 0.60 | HRH3 (0.69) | L3MBTL1CYP1A2HRH3SIGMAR1MEN1 | |
| SCHEMBL12826 | 0.60 | HRH3 (0.69) | L3MBTL1CYP1A2HRH3SIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |