Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542562 | 0.75 | NOTUM (0.42) | ALDH1A1KDM4EMAPTGAAL3MBTL1 | |
| SCHEMBL5546721 | 0.75 | NOTUM (0.38) | ALDH1A1KDM4EMAPTGAAMAPK1 | |
| SCHEMBL16241397 | 0.70 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTGAANPSR1 | |
| SCHEMBL2051536 | 0.64 | NOTUM (0.58) | ALDH1A1MAPTPTGS2LMNAGFER | |
| SCHEMBL65261 | 0.64 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTGAANPSR1 | |
| SCHEMBL9162666 | 0.63 | KDM4E (0.46) | ALDH1A1KDM4EMAPTGAANPSR1 | |
| SCHEMBL7306890 | 0.63 | CHRNB2 (0.42) | ALDH1A1L3MBTL1CYP3A4KAT2BNPC1 | |
| Hydrochloric Acid SCHEMBL379126 | 0.61 | ALDH1A1 (0.92) | ALDH1A1KDM4EMAPTGAANPSR1 | |
| Hydrochloric Acid SCHEMBL2443748 | 0.61 | ALDH1A1 (0.92) | ALDH1A1KDM4EMAPTGAANPSR1 | |
| Hydrochloric Acid SCHEMBL379125 | 0.61 | ALDH1A1 (0.92) | ALDH1A1KDM4EMAPTGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |