Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 5/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625446 | 1.00 | FDFT1 (0.40) | FDFT1RARBEEDALDH1A1MEN1 | |
| SCHEMBL8625391 | 0.96 | S1PR1 (0.41) | S1PR2S1PR1S1PR3S1PR4SPHK2 | |
| SCHEMBL8625397 | 0.96 | S1PR1 (0.41) | S1PR2S1PR1S1PR3S1PR4SPHK2 | |
| SCHEMBL8624983 | 0.93 | EED (0.40) | FDFT1EEDALDH1A1MAPTKDM4E | |
| SCHEMBL8624984 | 0.93 | EED (0.40) | FDFT1EEDALDH1A1MAPTKDM4E | |
| SCHEMBL8624891 | 0.87 | EED (0.39) | EEDALDH1A1MEN1KMT2AS1PR1 | |
| SCHEMBL8624889 | 0.87 | EED (0.39) | EEDALDH1A1MEN1KMT2AS1PR1 | |
| SCHEMBL8618052 | 0.87 | ENPP2 (0.45) | FDFT1RARBALDH1A1MEN1RARA | |
| SCHEMBL8618048 | 0.87 | ENPP2 (0.45) | FDFT1RARBALDH1A1MEN1RARA | |
| Potassium SCHEMBL9161975 | 0.86 | ENPP2 (0.44) | FDFT1RARBALDH1A1MEN1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712396-A | PHOSPHONOSULFONATE COMPOUNDS USED FOR INHIBITING CHOLESTEROL BIOSYNTHESIS AND ATHEROSCLEROSIS | MAGNIN DAVID R (US) | 1998-01-27 | — | — | US | disclosed |