Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.56 |
| ▸ | F2 | P00734 | 4/20 | 0.56 |
| ▸ | PLG | P00747 | 3/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.46 |
| ▸ | PROC | P04070 | 4/20 | 0.46 |
| ▸ | PLAT | P00750 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623066 | 0.88 | F10 (0.56) | F10F2PLGPRSS1PROC | |
| SCHEMBL8625631 | 0.88 | KCNH2 (0.43) | F10F2PLGPRSS1PROC | |
| SCHEMBL8627583 | 0.86 | F10 (0.49) | F10F2PLGPRSS1PROC | |
| SCHEMBL8625177 | 0.86 | F10 (0.44) | F10F2PLGKCNH2CYP3A4 | |
| SCHEMBL8625727 | 0.85 | F10 (0.43) | F10F2PLGPRSS1PROC | |
| SCHEMBL8622746 | 0.80 | KCNH2 (0.40) | KCNH2ALDH1A1 | |
| SCHEMBL8626509 | 0.78 | F10 (0.47) | F10F2PLGPRSS1PROC | |
| SCHEMBL2329218 | 0.78 | F10 (0.57) | F10KCNH2CYP3A4 | |
| SCHEMBL8623712 | 0.77 | F10 (0.45) | F10F2PLGPRSS1PROC | |
| SCHEMBL2326821 | 0.76 | F10 (0.51) | F10F2PLGPRSS1PROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731315-A | Substituted sulfonic acid n- (aminoiminomethyl)phenylalkyl!-azaheterocyclamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-03-24 | — | — | US | disclosed |