Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 14/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | PROC | P04070 | 1/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | CLPP | Q16740 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625177 | 0.94 | F10 (0.44) | KCNH2F10F2PLGCYP3A4 | |
| SCHEMBL8625528 | 0.88 | F10 (0.56) | KCNH2F10F2PLGCYP3A4 | |
| SCHEMBL8625727 | 0.87 | F10 (0.43) | KCNH2F10F2PLGCYP3A4 | |
| SCHEMBL8623066 | 0.85 | F10 (0.56) | KCNH2F10F2PLGCYP3A4 | |
| SCHEMBL2329218 | 0.84 | F10 (0.57) | KCNH2F10CYP3A4HTR1ADRD2 | |
| SCHEMBL8622746 | 0.82 | KCNH2 (0.40) | KCNH2HTR1ADRD2 | |
| SCHEMBL2326821 | 0.78 | F10 (0.51) | F10F2PLGPRSS1PROC | |
| SCHEMBL8626509 | 0.76 | F10 (0.47) | KCNH2F10F2PLGPRSS1 | |
| SCHEMBL2330488 | 0.74 | F10 (0.54) | F10F2PLGPRSS1PROC | |
| SCHEMBL8623712 | 0.74 | F10 (0.45) | KCNH2F10F2PLGPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731315-A | Substituted sulfonic acid n- (aminoiminomethyl)phenylalkyl!-azaheterocyclamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-03-24 | — | — | US | disclosed |