Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | PROC | P04070 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.33 |
| ▸ | PARG | Q86W56 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418409 | 0.89 | F10 (0.58) | F10F2PRSS1PLATPROC | |
| SCHEMBL8626509 | 0.88 | F10 (0.47) | F10F2PRSS1KCNH2PLAT | |
| SCHEMBL8623715 | 0.84 | F10 (0.41) | F10F2KCNH2PLATPROC | |
| SCHEMBL8625528 | 0.77 | F10 (0.56) | F10F2PRSS1KCNH2PLAT | |
| SCHEMBL8623066 | 0.76 | F10 (0.56) | F10F2PRSS1KCNH2PLAT | |
| SCHEMBL8622746 | 0.75 | KCNH2 (0.40) | KCNH2PARG | |
| SCHEMBL8625631 | 0.74 | KCNH2 (0.43) | F10F2PRSS1KCNH2PLAT | |
| SCHEMBL8625177 | 0.73 | F10 (0.44) | F10F2KCNH2PLG | |
| SCHEMBL2326821 | 0.73 | F10 (0.51) | F10F2PRSS1PROCPLG | |
| SCHEMBL2330834 | 0.72 | F10 (0.73) | F10F2PRSS1PLATPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731315-A | Substituted sulfonic acid n- (aminoiminomethyl)phenylalkyl!-azaheterocyclamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-03-24 | — | — | US | disclosed |