Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.60 |
| ▸ | CES1 | P23141 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.43 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.43 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.43 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284994 | 0.84 | CES1 (0.47) | CES2CES1TSHRALOX15L3MBTL1 | |
| SCHEMBL2462551 | 0.84 | CES1 (0.47) | CES2CES1TSHRALOX15L3MBTL1 | |
| SCHEMBL8346950 | 0.79 | CES2 (0.65) | CES2CES1TSHRALOX15CYP1A2 | |
| SCHEMBL14119105 | 0.79 | CES2 (0.65) | CES2CES1TSHRALOX15CYP1A2 | |
| SCHEMBL33953 | 0.79 | CES2 (0.65) | CES2CES1TSHRALOX15CYP1A2 | |
| SCHEMBL9971796 | 0.79 | CES2 (0.65) | CES2CES1TSHRALOX15CYP1A2 | |
| SCHEMBL14119103 | 0.79 | CES2 (0.65) | CES2CES1TSHRALOX15CYP1A2 | |
| SCHEMBL9099733 | 0.75 | CES2 (0.60) | CES2CES1TSHRMAPTMEN1 | |
| SCHEMBL912515 | 0.75 | CES2 (1.00) | CES2CES1TSHRALOX15L3MBTL1 | |
| SCHEMBL6493746 | 0.75 | CES2 (0.60) | CES2CES1TSHRALOX15CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | disclosed |