SCHEMBL8625641

SCHEMBL8625641

CC(=O)NC(C)c1nnn[nH]1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ACACB O00763 12/20 0.31
ACACA Q13085 2/20 0.31
PPARD Q03181 4/20 0.31
PPARA Q07869 4/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15764466 0.78 ALDH1A1 (0.32)
SCHEMBL4455551 0.75 KDM4E (0.38)
SCHEMBL15764481 0.74 ALDH1A1 (0.32)
SCHEMBL8232997 0.72 TSHR (0.36)
SCHEMBL15592767 0.71 PARP1 (0.30)
SCHEMBL13995763 0.70 L3MBTL1 (0.40) ACACBL3MBTL1
SCHEMBL4457143 0.70
SCHEMBL4457146 0.70
SCHEMBL13091637 0.69 ATM (0.47) ACACBPPARDPPARAL3MBTL1
SCHEMBL6128263 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE35754-E FOR TREATING BACTERIAL INFECTIONS HOECHST AKTIENGESELLSCHAFT (DE) 1998-03-24 US disclosed
US-5710146-A ANTIBIOTICS FOR BACTERICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1998-01-20 US disclosed
US-5089490-A Cephem derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-18 US disclosed
US-4758556-A Cephem derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1988-07-19 US disclosed
US-4399131-A Cephem derivatives HOECHST AG (DE) 1983-08-16 US disclosed
US-4278793-A ANTIBIOTICS, BACTERICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1981-07-14 US disclosed