SCHEMBL8625684

SCHEMBL8625684

C=CC(F)(F)C(=O)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2407437 0.80
SCHEMBL4791763 0.75
SCHEMBL22189211 0.73 ALDH1A1 (0.30)
SCHEMBL10455715 0.73
SCHEMBL7791433 0.73
SCHEMBL9396943 0.73
Hydrochloric Acid SCHEMBL9396950 0.73
SCHEMBL15412777 0.71 LMNA (0.33)
SCHEMBL12626668 0.69 ALDH1A1 (0.36)
SCHEMBL6063951 0.69 LMNA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0614873-B1 Hexafluoropropylene oxide compounds and a method of making same SHINETSU CHEMICAL CO (JP) 1998-06-10 EP disclosed
US-5414119-A Hexafluoropropylene oxide compounds and a method of making same SHIN ETSU CHEMICAL CO., LTD. (JP) 1995-05-09 US disclosed
EP-0614873-A1 Hexafluoropropylene oxide compounds and a method of making same Shin-Etsu Chemical Co., Ltd. (JP) 1994-09-14 EP disclosed