Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | CTRC | Q99895 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2204108 | 0.77 | — | — | |
| SCHEMBL3434244 | 0.76 | CHRNB2 (0.44) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL16767764 | 0.74 | CHRNB2 (0.35) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL9327568 | 0.74 | CHRNB2 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL3990357 | 0.70 | — | — | |
| SCHEMBL20865484 | 0.69 | — | — | |
| SCHEMBL3985111 | 0.68 | CHRNB2 (0.45) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL906504 | 0.68 | CHRNB2 (0.38) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL22789099 | 0.68 | — | — | |
| SCHEMBL11465941 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567430-B1 | Substituted 1-Hydroxy-2,6-Diaryl-4-Piperidone Ketal Stabilizers | CIBA GEIGY AG (CH) | 1998-02-18 | — | — | EP | disclosed |
| EP-0512951-B1 | Substituted 1-oxy-4-acyloxypiperidine and 1-oxy-4-acylaminopiperidine stabilizers | CIBA GEIGY AG (CH) | 1997-07-23 | — | — | EP | disclosed |
| EP-0512948-B1 | Substituted 1-hydroxy-2,6-Di-aryl-4-acyloxypiperidines or 1-hydroxy-2,6-diaryl-4-acyl-aminopiperidines and stabilized compositions | CIBA GEIGY AG (CH) | 1996-08-28 | — | — | EP | disclosed |
| US-5371125-A | Process stabilizers; discoloration inhibition; oxidation and heat resistance | CIBA-GEIGY CORPORATION (US) | 1994-12-06 | — | — | US | disclosed |
| US-5262538-A | Stabilizers for heat, oxidation and radiation resistance | CIBA-GEIGY CORPORATION (US) | 1993-11-16 | — | — | US | disclosed |
| EP-0567430-A1 | Substituted 1-Hydroxy-2,6-Diaryl-4-Piperidone Ketal Stabilizers | CIBA-GEIGY AG (CH) | 1993-10-27 | — | — | EP | disclosed |
| US-5235056-A | Discoloration inhibitors | CIBA-GEIGY CORPORATION (US) | 1993-08-10 | — | — | US | disclosed |
| US-5185448-A | Providing melt flow stability to polymers during processing | CIBA-GEIGY CORPORATION (US) | 1993-02-09 | — | — | US | disclosed |
| US-5180829-A | Stabilizers against oxygen, heat and actinic radiation | CIBA-GEIGY CORPORATION (US) | 1993-01-19 | — | — | US | disclosed |
| EP-0512948-A1 | Substituted 1-hydroxy-2,6-Di-aryl-4-acyloxypiperidines or 1-hydroxy-2,6-diaryl-4-acyl-aminopiperidines and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-11 | — | — | EP | disclosed |
| EP-0512951-A1 | Substituted 1-oxy-4-acyloxypiperidine and 1-oxy-4-acylaminopiperidine stabilizers | CIBA-GEIGY AG (CH) | 1992-11-11 | — | — | EP | disclosed |