SCHEMBL906504

SCHEMBL906504

C=CCC1CCCN1C=C

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.38
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA7 P36544 1/20 0.38
CHRNA4 P43681 1/20 0.38
NOS1 P29475 2/20 0.32
NOS2 P35228 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28068406 0.83 CHRNB2 (0.36) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL9797379 0.78
SCHEMBL14509634 0.78
SCHEMBL7147030 0.78 CHRNB2 (0.41) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL3990357 0.76
SCHEMBL30481698 0.75 PSEN1 (0.32)
SCHEMBL2204108 0.74
SCHEMBL8854904 0.74
SCHEMBL5139447 0.74
SCHEMBL22789099 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216260-A1 HAIR TREATMENT COMPOSITIONS THAT IMPART SHINE AND LUSTER L'OREAL (FR) 2024-07-04 US disclosed
EP-4392003-A1 PERSONAL CARE COMPOSITIONS Colgate-Palmolive Company (US) 2024-07-03 EP disclosed
US-20240197597-A1 HAIR STYLING COMPOSITIONS L'OREAL (FR) 2024-06-20 US disclosed
WO-2024129386-A1 HAIR TREATMENT COMPOSITIONS THAT IMPART SHINE AND LUSTER L'OREAL (FR) 2024-06-20 WO disclosed
US-20240180813-A1 AMINOSILOXANE ESTER COPOLYMER AND METHODS FOR THE PREPARATION AND USE OF THE COPOLYMER DOW SILICONES CORP (US) 2024-06-06 US disclosed
US-11998628-B2 Personal care compositions COLGATE-PALMOLIVE COMPANY (US) 2024-06-04 US disclosed
EP-4363488-A1 AMINOSILOXANE ESTER COPOLYMER AND METHODS FOR THE PREPARATION AND USE OF THE COPOLYMER Dow Silicones Corporation (US) 2024-05-08 EP disclosed
US-20240082129-A1 HAIR COLORING COMPOSITIONS SUITABLE FOR FACIAL HAIR L'OREAL (FR) 2024-03-14 US disclosed
US-20240041751-A1 HAIR COLORING WITH COCONUT OIL L'OREAL (FR) 2024-02-08 US disclosed
WO-2024026212-A1 HAIR COLORING WITH COCONUT OIL L'OREAL (FR) 2024-02-01 WO disclosed
WO-1998018435-A2 CONDITIONING SHAMPOO COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 1998-05-07 WO disclosed
WO-1998013011-A1 SHAMPOO COMPOSITION UNILEVER PLC (GB) 1998-04-02 WO disclosed
US-5720964-A SHAMPOO COMPRISING ANIONIC SURFACTANT, NONIONIC POLYDIMETHYLSILOXANE, CATIONIC ANTIDEPOSITING AGENT AND WATER; LOW VISCOSITY, CONDITIONING CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1998-02-24 US disclosed
WO-1998005296-A1 SHAMPOO COMPOSITIONS AND METHOD UNILEVER PLC (GB) 1998-02-12 WO disclosed
EP-0820266-A1 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 1998-01-28 EP disclosed
WO-1997039096-A1 ANTIMICROBIAL HAIR TREATMENT COMPOSITION OLIN CORPORATION (US) 1997-10-23 WO disclosed
EP-0800814-A2 Antimicrobial hair treatment composition UNILEVER PLC (GB) 1997-10-15 EP disclosed
WO-1996031188-A1 HAIR TREATMENT COMPOSITIONS UNILEVER PLC (GB) 1996-10-10 WO disclosed
EP-0722309-A1 HAIR CONDITIONING COMPOSITION UNILEVER PLC (GB) 1996-07-24 EP disclosed
WO-1995009599-A1 HAIR CONDITIONING COMPOSITION UNILEVER PLC (GB) 1995-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240180813-A1 AMINOSILOXANE ESTER COPOLYMER AND METHODS FOR THE PREPARATION AND USE OF THE COPOLYMER POLR1C, SUCLG1, SRM CHRNB2 4803/4885CHRNB4 4723/4885CHRNA3 4403/4885
US-20240041751-A1 HAIR COLORING WITH COCONUT OIL SHH, SMO, SPOP CHRNB2 1075/4885CHRNB4 1045/4885CHRNA3 1142/4885
US-20240197597-A1 HAIR STYLING COMPOSITIONS PIK3C3, POLR1C, ALKBH3 CHRNB2 4320/4885CHRNB4 4420/4885CHRNA3 3634/4885
US-20240216260-A1 HAIR TREATMENT COMPOSITIONS THAT IMPART SHINE AND LUSTER DNER, PHOSPHO1, SGMS1 CHRNB2 1929/4885CHRNB4 1423/4885CHRNA3 1737/4885
US-20240082129-A1 HAIR COLORING COMPOSITIONS SUITABLE FOR FACIAL HAIR TYR, PNMT, PANK2 CHRNB2 1925/4885CHRNB4 1789/4885CHRNA3 2947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.