Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 5/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625916 | 0.79 | SLC6A2 (0.51) | SLC6A2SLC6A3SLC6A4ADRB2PNMT | |
| SCHEMBL4691720 | 0.79 | SLC6A3 (0.62) | SLC6A2SLC6A3SLC6A4ADRB2PNMT | |
| SCHEMBL8625124 | 0.79 | HTR2A (0.50) | CYP2A6SLC6A2SLC6A3SLC6A4CNR1 | |
| Hydrochloric Acid SCHEMBL3371509 | 0.77 | SLC6A2 (0.60) | SLC6A2SLC6A3SLC6A4ADRB2CNR1 | |
| SCHEMBL8621289 | 0.74 | SLC6A2 (0.56) | SLC6A2SLC6A3SLC6A4ADRB2CNR1 | |
| SCHEMBL8619441 | 0.74 | SLC6A2 (0.56) | SLC6A2SLC6A3SLC6A4ADRB2CNR1 | |
| SCHEMBL8622251 | 0.74 | PNMT (0.60) | SLC6A2SLC6A3SLC6A4ADRB2PNMT | |
| SCHEMBL200500 | 0.74 | SLC6A2 (0.56) | SLC6A2SLC6A3SLC6A4PNMTCNR1 | |
| SCHEMBL8622270 | 0.73 | FDFT1 (0.73) | P2RX3CNR1CNR2FDFT1 | |
| SCHEMBL8622953 | 0.73 | SLC6A3 (0.55) | SLC6A2SLC6A3SLC6A4ADRB2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5777150-A | Substituted amic acid derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-07-07 | — | — | US | disclosed |