⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10985887 | 0.86 | — | — | |
| SCHEMBL8629246 | 0.59 | — | — | |
| SCHEMBL7403003 | 0.59 | — | — | |
| SCHEMBL4505762 | 0.50 | — | — | |
| SCHEMBL242967 | 0.50 | — | — | |
| SCHEMBL179843 | 0.50 | ALOX15 (1.00) | — | |
| SCHEMBL3975418 | 0.50 | ALOX15 (1.00) | — | |
| SCHEMBL11541738 | 0.48 | ALOX15 (0.93) | — | |
| SCHEMBL11501587 | 0.48 | ALOX15 (0.93) | — | |
| SCHEMBL22691893 | 0.45 | ALOX15 (0.81) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548338-B1 | PROCESS FOR THE PREPARATION OF CEPHALOSPORINS INTERMEDIATES | ANTIBIOTICOS SPA (IT) | 1996-10-23 | — | — | EP | claimed |
| US-5387679-A | Useful intermediates in synthesis of Cefazolin and Cefazedone | ANTIBIOTICOS S.P.A. (IT) | 1995-02-07 | — | — | US | claimed |
| US-4385178-A | REACTION OF A CEPHALOSPORANIC ACID WITH A THIOL COMPOUND IN THE PRESENCE OF BORON TRIFLUORIDE | TOYAMA CHEMICAL CO., LTD. (JP) | 1983-05-24 | — | — | US | claimed |
| US-4317907-A | ANHYDROUS CONDITIONS IN THE PRESENCE OF BOREN TRIFLUORIDE OR ONE OF ITS COMPLEXES | TOYAMA CHEMICAL CO., LTD. (JP) | 1982-03-02 | — | — | US | claimed |
| US-4205166-A | 7-Substituted-3-aminoalkyl-, acylaminoalkyl-, or hydroxyalkyl-substituted heterocyclic thiomethyl-3-cephem-4-carboxylic acid derivatives and preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-05-27 | — | — | US | claimed |
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| EP-0548338-B1 | PROCESS FOR THE PREPARATION OF CEPHALOSPORINS INTERMEDIATES | ANTIBIOTICOS SPA (IT) | 1996-10-23 | — | — | EP | disclosed |
| US-5387679-A | Useful intermediates in synthesis of Cefazolin and Cefazedone | ANTIBIOTICOS S.P.A. (IT) | 1995-02-07 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4529802-A | A carboxylated thiazole oxime compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-07-16 | — | — | US | disclosed |
| EP-0025199-B1 | CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-31 | — | — | EP | disclosed |
| EP-0088454-A2 | New starting compounds for preparing cephem compounds and processes for their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-09-14 | — | — | EP | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4394384-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-07-19 | — | — | US | disclosed |
| US-4366153-A | CEPHALOSPORINS; ANTIBIOTICS; BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-12-28 | — | — | US | disclosed |
| US-4341775-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-07-27 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |
| EP-0025199-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-03-18 | — | — | EP | disclosed |