Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.93 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179843 | 0.96 | ALOX15 (1.00) | ALOX15ACE2KEAP1SMN1; SMN2SIGMAR1 | |
| SCHEMBL3975418 | 0.96 | ALOX15 (1.00) | ALOX15ACE2KEAP1SMN1; SMN2SIGMAR1 | |
| SCHEMBL242967 | 0.96 | — | — | |
| SCHEMBL11541738 | 0.93 | ALOX15 (0.93) | ALOX15ACE2KEAP1SMN1; SMN2SIGMAR1 | |
| SCHEMBL1306821 | 0.91 | ALOX15 (0.77) | ALOX15ACE2KEAP1SMN1; SMN2SIGMAR1 | |
| SCHEMBL13661134 | 0.88 | ALOX15 (0.72) | ALOX15ACE2KEAP1SMN1; SMN2SIGMAR1 | |
| SCHEMBL8735020 | 0.87 | ALOX15 (0.81) | ALOX15ACE2KEAP1SMN1; SMN2SIGMAR1 | |
| SCHEMBL22691893 | 0.87 | ALOX15 (0.81) | ALOX15ACE2KEAP1SMN1; SMN2SIGMAR1 | |
| SCHEMBL1307205 | 0.86 | KEAP1 (0.70) | ALOX15ACE2KEAP1SMN1; SMN2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3671864 | 0.84 | ALOX15 (0.77) | ALOX15ACE2KEAP1SMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10995077-B2 | Process to prepare higher ethylene amines and ethylene amine derivatives | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2021-05-04 | — | — | US | disclosed |
| US-20190047971-A1 | PROCESS TO PREPARE HIGHER ETHYLENE AMINES AND ETHYLENE AMINE DERIVATIVES | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2019-02-14 | — | — | US | disclosed |
| WO-2017137530-A1 | PROCESS TO PREPARE HIGHER ETHYLENE AMINES AND ETHYLENE AMINE DERIVATIVES | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2017-08-17 | — | — | WO | disclosed |
| US-4166827-A | DENTAL PLAQUE | COOPER LABORATORIES, INC. (US) | 1979-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10995077-B2 | Process to prepare higher ethylene amines and ethylene amine derivatives | H1-5, H1-4, PNMT | ALOX15 1441/4885ACE2 3284/4885KEAP1 274/4885 |
| US-20190047971-A1 | PROCESS TO PREPARE HIGHER ETHYLENE AMINES AND ETHYLENE AMINE DERIVATIVES | H1-5, H1-4, PNMT | ALOX15 1441/4885ACE2 3284/4885KEAP1 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.