Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 8/20 | 0.56 |
| ▸ | FNTB | P49356 | 8/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623007 | 0.89 | FNTA (0.67) | FNTAFNTBNPSR1CA2CA1 | |
| SCHEMBL8621284 | 0.88 | FNTA (0.52) | FNTAFNTBCA2CA1 | |
| SCHEMBL8623835 | 0.84 | FNTA (0.52) | FNTAFNTBNPSR1CA2CA1 | |
| SCHEMBL8623763 | 0.79 | FNTA (0.57) | FNTAFNTBNPSR1CA2CA1 | |
| SCHEMBL8623996 | 0.78 | FNTA (0.60) | FNTAFNTBNPSR1CA2CA1 | |
| SCHEMBL8626201 | 0.76 | FNTA (0.48) | FNTAFNTBCA2CA1 | |
| SCHEMBL2324069 | 0.75 | FNTA (0.62) | FNTAFNTBNPSR1CA2CA1 | |
| SCHEMBL9828951 | 0.75 | FNTA (0.62) | FNTAFNTBNPSR1CA2CA1 | |
| SCHEMBL8626764 | 0.73 | FNTA (0.60) | FNTAFNTB | |
| SCHEMBL6624887 | 0.71 | FNTA (0.66) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842150-A1 | NOVEL FARNESYL TRANSFERASE INHIBITORS, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID INHIBITORS | Aventis Pharma S.A. (FR) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997003047-A1 | NOVEL FARNESYL TRANSFERASE INHIBITORS, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID INHIBITORS | Rhône-Poulenc Rorer S.A. (FR) | 1997-01-30 | — | — | WO | disclosed |