Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945230 | 0.92 | PRKCI (0.48) | EDNRAEDNRB | |
| SCHEMBL8622871 | 0.91 | EDNRA (0.51) | EDNRAEDNRB | |
| SCHEMBL8623907 | 0.90 | PRKCI (0.46) | EDNRAEDNRB | |
| SCHEMBL7538071 | 0.88 | EDNRA (0.54) | EDNRAEDNRB | |
| SCHEMBL8620432 | 0.87 | EDNRA (0.51) | EDNRAEDNRB | |
| SCHEMBL8622696 | 0.86 | SCN9A (0.44) | EDNRA | |
| SCHEMBL8622689 | 0.80 | EDNRA (0.52) | EDNRAEDNRB | |
| SCHEMBL8624525 | 0.79 | MAPT (0.47) | — | |
| SCHEMBL7534309 | 0.79 | EDNRA (0.55) | EDNRAEDNRB | |
| SCHEMBL7533979 | 0.78 | EDNRA (0.55) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817693-A | Endothelin receptor antagonists | SMITHKLINE BEECHAM CORPORATION | 1998-10-06 | — | — | US | disclosed |
| US-5719182-A | TREATING HYPERTENSION, RENAL FAILURE, CEREBROVASCULAR DISEASE | SMITHKLINE BEECHAM CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |