Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401792 | 0.85 | POLB (0.37) | POLBSMN1; SMN2 | |
| SCHEMBL10597320 | 0.85 | POLB (0.37) | POLBSMN1; SMN2 | |
| SCHEMBL10594005 | 0.85 | POLB (0.37) | POLBSMN1; SMN2 | |
| SCHEMBL8627497 | 0.85 | POLB (0.39) | POLBSMN1; SMN2 | |
| SCHEMBL8626068 | 0.83 | SMN1; SMN2 (0.33) | POLBSMN1; SMN2 | |
| SCHEMBL9468060 | 0.78 | KMT2A (0.34) | POLBSMN1; SMN2 | |
| SCHEMBL10596773 | 0.77 | SMN1; SMN2 (0.33) | POLBSMN1; SMN2 | |
| SCHEMBL10802418 | 0.77 | SMN1; SMN2 (0.33) | POLBSMN1; SMN2 | |
| SCHEMBL10594166 | 0.75 | GAA (0.32) | POLBSMN1; SMN2 | |
| SCHEMBL10595798 | 0.75 | MEN1 (0.33) | POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503597-B1 | Penam derivatives and processes for producing the same | OTSUKA KAGAKU KK (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5599925-A | BACTERICIDES | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-02-04 | — | — | US | disclosed |
| US-5300497-A | Broad spectrum antibiotics and bactericides; stable to beta-lactamase; effective against antibiotic-resistant bacteria | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5185330-A | Penicillins/ad/ | TOYAMA CHEMICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| EP-0503597-A2 | Penam derivatives and processes for producing the same | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1992-09-16 | — | — | EP | disclosed |