Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28354853 | 0.77 | HDAC4 (0.41) | LMNAOPRM1OPRL1HSD11B1KMT2A | |
| SCHEMBL4451679 | 0.77 | HDAC4 (0.41) | LMNAOPRM1OPRL1HSD11B1KMT2A | |
| Hydrochloric Acid SCHEMBL27395419 | 0.77 | CES2 (0.35) | L3MBTL1LMNANAPRTP4HTMOPRM1 | |
| SCHEMBL27731834 | 0.73 | AKR1C1 (0.37) | NAPRTHSD11B1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11438176 | 0.73 | — | — | |
| SCHEMBL29777956 | 0.72 | SLC6A2 (0.36) | LMNAP4HTMOPRM1OPRD1OPRK1 | |
| SCHEMBL22911623 | 0.72 | SLC6A2 (0.36) | LMNAP4HTMOPRM1OPRD1OPRK1 | |
| SCHEMBL4630348 | 0.72 | GRIN2B (0.33) | OPRM1OPRD1OPRK1OPRL1KDM4E | |
| SCHEMBL14685895 | 0.71 | GRIN1 (0.35) | LMNAP4HTMOPRM1OPRD1OPRK1 | |
| SCHEMBL5969621 | 0.71 | GRIN1 (0.35) | LMNAP4HTMOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753648-A | THREATING DISEASES CAUSED BY RENAL REABSORPTION OF WATER | AMERICAN CYANAMID COMPANY (US) | 1998-05-19 | — | — | US | disclosed |
| US-5700796-A | USEFUL FOR TREATING CONGESTIVE HEART FAILURE, DISEASE CONDITIONS WITH EXCESS RENAL WATER REABSORPTION AND CONDITIONS WITH INCREASED VASULAR RESISTANCE AND CORONARY VASOCONSTRICTION | AMERICAN CYANAMID COMPANY (US) | 1997-12-23 | — | — | US | disclosed |