Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 5/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451679 | 1.00 | HDAC4 (0.41) | HDAC4AKR1C1LMNAHTTHDAC9 | |
| SCHEMBL29120630 | 0.86 | HDAC4 (0.39) | HDAC4AKR1C1LMNAHTTHDAC9 | |
| SCHEMBL15529967 | 0.86 | HDAC4 (0.39) | HDAC4AKR1C1LMNAHTTHDAC9 | |
| SCHEMBL3836530 | 0.86 | HDAC4 (0.39) | HDAC4AKR1C1HDAC9HSD11B1OPRM1 | |
| SCHEMBL9458297 | 0.86 | APP (0.33) | — | |
| SCHEMBL9029796 | 0.84 | HSD11B1 (0.38) | LMNAHSD11B1OPRM1OPRL1 | |
| SCHEMBL2783202 | 0.84 | TSHR (0.40) | — | |
| SCHEMBL29531155 | 0.84 | HDAC4 (0.38) | HDAC4AKR1C1LMNAHDAC9MAPK1 | |
| SCHEMBL28878362 | 0.81 | HDAC4 (0.33) | HDAC4 | |
| SCHEMBL28916077 | 0.81 | HDAC4 (0.33) | HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500520-A | Immunogenic compositions comprising antigen and an adjuvant comprising Al-MOF | 圣康丁昂伊夫利纳凡尔赛大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-110719783-A | Pharmaceutical composition | 阿特密斯株式会社 | 2020-01-21 | — | — | CN | disclosed |