Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cefaclor Anhydrous. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | NR1I2 | O75469 | 1/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 1.00 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.77 |
| ▸ | BLM | P54132 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cefaclor Anhydrous SCHEMBL49912 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAPTKMT2AKDM4E | |
| Cefaclor Anhydrous SCHEMBL33540 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAPTKMT2AKDM4E | |
| Cefaclor Anhydrous SCHEMBL8524989 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAPTKMT2AKDM4E | |
| Cefaclor Anhydrous SCHEMBL8943624 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAPTKMT2AKDM4E | |
| Cefaclor Anhydrous SCHEMBL6155629 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAPTKMT2AKDM4E | |
| Cefaclor Anhydrous SCHEMBL16072812 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAPTKMT2AKDM4E | |
| Cefaclor Anhydrous SCHEMBL8478823 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAPTKMT2AKDM4E | |
| Cefaclor Anhydrous SCHEMBL1006419 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAPTKMT2AKDM4E | |
| Cefaclor Anhydrous SCHEMBL8626208 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAPTKMT2AKDM4E | |
| Cefaclor Anhydrous SCHEMBL27281884 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547646-B1 | Crystalline form of a cephalosporin antibiotic | OPOS BIOCHIMICA SRL (IT) | 1998-06-03 | — | — | EP | disclosed |
| US-5693790-A | FORMED BY TREATING CEFACLOR WITH MINERAL OR ORGANIC ACID IN MIXTURE OF WATER AND ALCOHOL | BIOCHIMICA OPOS SPA (IT) | 1997-12-02 | — | — | US | disclosed |
| US-5589593-A | CRYSTALLIZATION OF CEFACLOR AND FORMATION OF THE HYDRATE, STABILITY | BIOCHIMICA OPOS SPA (IT) | 1996-12-31 | — | — | US | disclosed |
| EP-0547646-A2 | Crystalline form of a cephalosporin antibiotic | BIOCHIMICA OPOS SPA (IT) | 1993-06-23 | — | — | EP | disclosed |
| US-4089955-A | ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1978-05-16 | — | — | US | disclosed |