Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | STS | P08842 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Phenoxyaniline SCHEMBL29143118 | 0.88 | PBRM1 (0.69) | PBRM1MAOBAKR1C3NPC1STS | |
| SCHEMBL311673 | 0.87 | PBRM1 (0.61) | PBRM1MAOBAKR1C3NPC1STS | |
| SCHEMBL29436300 | 0.87 | PBRM1 (0.61) | PBRM1MAOBAKR1C3NPC1STS | |
| SCHEMBL9098795 | 0.87 | PBRM1 (0.67) | PBRM1MAOBAKR1C3NPC1STS | |
| SCHEMBL3620652 | 0.86 | MEN1 (0.60) | PBRM1MAOBAKR1C3NPC1STS | |
| SCHEMBL8903317 | 0.85 | PBRM1 (0.59) | PBRM1MAOBAKR1C3NPC1STS | |
| SCHEMBL8543799 | 0.84 | MAOB (0.68) | PBRM1MAOBAKR1C3NPC1MEN1 | |
| SCHEMBL309443 | 0.84 | TNKS (0.61) | PBRM1MAOBAKR1C3NPC1STS | |
| SCHEMBL8375630 | 0.84 | PBRM1 (0.64) | PBRM1MAOBAKR1C3NPC1STS | |
| SCHEMBL8734462 | 0.82 | PBRM1 (0.70) | PBRM1MAOBNPC1STSKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710334-A | PENDANT ETHER GROUPS, POLYIMIDES WITH IMPROVED SOLUBILITY, MELT FLOW STABILITY, PROCESSABILITY | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-01-20 | — | — | US | disclosed |
| US-5480965-A | BASED ON A NOVEL DIAMINO COMPOUND DERIVED FROM BENZOPHENONE STRUCTURE; FIBER REINFORCEMENT | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0639621-A2 | Polyimide-based resin composition | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-02-22 | — | — | EP | disclosed |