SCHEMBL309443

SCHEMBL309443

Nc1cccc(Oc2cccc(C(=O)c3ccc(Oc4ccc(C(=O)c5cccc(Oc6cccc(N)c6)c5)cc4)cc3)c2)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 1/20 0.61
PARP15 Q460N3 1/20 0.61
PARP14 Q460N5 1/20 0.61
PARP10 Q53GL7 1/20 0.61
TNKS2 Q9H2K2 1/20 0.61
PARP2 Q9UGN5 1/20 0.61
PBRM1 Q86U86 1/20 0.59
MAOB P27338 1/20 0.58
STS P08842 6/20 0.55
SRD5A2 P31213 1/20 0.53
AKR1C3 P42330 1/20 0.53
POLB P06746 2/20 0.53
ALDH1A1 P00352 2/20 0.53
MITF O75030 2/20 0.51
NPC1 O15118 1/20 0.51
LMNA P02545 1/20 0.51
MEN1 O00255 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
GFER P55789 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29363911 0.97 PBRM1 (0.59) TNKSPARP15PARP14PARP10TNKS2
SCHEMBL203908 0.97 PBRM1 (0.59) TNKSPARP15PARP14PARP10TNKS2
SCHEMBL8375630 0.97 PBRM1 (0.64) TNKSPARP15PARP14PARP10TNKS2
SCHEMBL204441 0.95 MAOB (0.63) TNKSPARP15PARP14PARP10TNKS2
SCHEMBL29394233 0.95 MAOB (0.63) TNKSPARP15PARP14PARP10TNKS2
SCHEMBL29362975 0.95 MAOB (0.63) TNKSPARP15PARP14PARP10TNKS2
SCHEMBL8962593 0.95 MAOB (0.63) TNKSPARP15PARP14PARP10TNKS2
SCHEMBL204289 0.95 MAOB (0.63) TNKSPARP15PARP14PARP10TNKS2
SCHEMBL8543799 0.94 MAOB (0.68) TNKSPARP15PARP14PARP10TNKS2
SCHEMBL311673 0.93 PBRM1 (0.61) TNKSPARP15PARP14PARP10TNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 263 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INST SCI & TECH (KR) 2018-03-08 US claimed
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-07-07 US claimed
EP-2940015-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT Korea Advanced Institute of Science and Technology (KR) 2015-11-04 EP claimed
US-20150045481-A1 Asymmetric Diamine Compounds Containing Two Functional Groups and Polymers Therefrom KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-02-12 US claimed
US-5459233-A High temperature engineering aromatic polyimides MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-10-17 US claimed
US-5288843-A Polymerizing 4,4'-bis(3-aminophenoxy)biphenyl, pyromellitic dianhydride and a different aromaticdiamine; engineering plastics; molding mateials; aerospace; heat resistance; melt processibility MITSUI TOATSU CHEMICALS, INC. (JP) 1994-02-22 US claimed
EP-4401112-A1 SEMICONDUCTOR APPARATUS AND METHOD FOR MANUFACTURING SEMICONDUCTOR APPARATUS University of Tsukuba (JP) 2024-07-17 EP disclosed
US-20240227373-A1 MULTILAYER BODY OF INORGANIC SUBSTRATE AND TRANSPARENT HEAT-RESISTANT POLYMER FILM TOYOBO CO., LTD. (JP) 2024-07-11 US disclosed
US-20240227363-A1 LAMINATE OF INORGANIC SUBSTRATE AND HEAT-RESISTANT POLYMER FILM TOYOBO CO., LTD. (JP) 2024-07-11 US disclosed
CN-113950409-B Laminate body 东洋纺株式会社 2024-06-28 CN disclosed
WO-2024135780-A1 POLYIMIDE FILM, MULTILAYER BODY, FLEXIBLE ELECTRONIC DEVICE AND METHOD FOR PRODUCING FLEXIBLE ELECTRONIC DEVICE 東洋紡株式会社 2024-06-27 WO disclosed
EP-4389419-A1 TRANSPARENT HEAT-RESISTANT LAMINATED FILM TOYOBO CO., LTD. (JP) 2024-06-26 EP disclosed
CN-118076482-A Laminate with protective film-assisted release tape 东洋纺株式会社 2024-05-24 CN disclosed
EP-0488604-A2 Readily processable polyimide, preparation process of polyimide, and resin composition of polyimide MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-06-03 EP disclosed
EP-0472402-A1 Readily processable polyimide and preparation process of same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-02-26 EP disclosed
EP-0462282-A1 POLYIMIDE MOLDING MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-12-27 EP disclosed
EP-0459801-A2 Readily processable polyimide and preparation process of same MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-12-04 EP disclosed
EP-0431789-A2 Preparation process of polyimide MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-06-12 EP disclosed
EP-0430430-A2 Polyimide MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-06-05 EP disclosed
EP-0367482-A1 Polyimides and process for the preparation thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-05-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150045481-A1 Asymmetric Diamine Compounds Containing Two Functional Groups and Polymers Therefrom AOC1, INMT, PRMT6 TNKS 1946/4885PARP15 1078/4885PARP14 1375/4885
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT RICTOR, SGTA, SLC43A1 TNKS 972/4885PARP15 1201/4885PARP14 756/4885
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT SGTA, RICTOR, SLC43A1 TNKS 1486/4885PARP15 1060/4885PARP14 706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.