SCHEMBL8626261

SCHEMBL8626261

COCC(=O)Nc1c(C)cccc1C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.59
KMT2A Q03164 4/20 0.59
CYP1A2 P05177 2/20 0.59
CYP2C9 P11712 2/20 0.59
CYP2C19 P33261 2/20 0.59
NFKB1 P19838 1/20 0.59
MAPT P10636 4/20 0.56
SCN3A Q9NY46 3/20 0.56
LMNA P02545 3/20 0.56
SCN1A P35498 2/20 0.56
SCN2A Q99250 2/20 0.56
ALDH1A1 P00352 2/20 0.56
MAPK1 P28482 2/20 0.56
HDAC3 O15379 1/20 0.56
HDAC4 P56524 1/20 0.56
HDAC1 Q13547 1/20 0.56
HDAC7 Q8WUI4 1/20 0.56
HDAC2 Q92769 1/20 0.56
HDAC10 Q969S8 1/20 0.56
HDAC11 Q96DB2 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8622854 0.98 MEN1 (0.57) MEN1KMT2ACYP1A2CYP2C9CYP2C19
SCHEMBL21765473 0.84 MEN1 (0.57) MEN1KMT2ACYP1A2CYP2C9CYP2C19
SCHEMBL11723693 0.81 HPGD (0.51) KMT2ACYP2C19MAPTLMNAALDH1A1
SCHEMBL2093587 0.81 LMNA (0.61) MEN1KMT2AMAPTLMNAALDH1A1
SCHEMBL7547745 0.80 SMN1; SMN2 (0.71) MEN1KMT2AMAPTLMNAALDH1A1
SCHEMBL11085927 0.79 CYP2C19 (0.46) CYP1A2CYP2C19MAPTLMNAALDH1A1
SCHEMBL10567645 0.79 MAPT (0.66) MEN1KMT2ACYP1A2CYP2C9CYP2C19
SCHEMBL5892506 0.79 KMT2A (0.65) MEN1KMT2ACYP1A2CYP2C9CYP2C19
SCHEMBL28164480 0.78 MEN1 (0.53) MEN1KMT2ACYP1A2CYP2C9CYP2C19
Glycinexylidide SCHEMBL4107220 0.77 LMNA (0.65) MEN1KMT2ACYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113979880-A Novel method for preparing dimethachlor 上海农帆生物科技有限公司 2022-01-28 CN claimed
CN-114716341-B Method for preparing dimethenamid by one-pot method 上海农帆生物科技有限公司 2024-05-03 CN disclosed
CN-111995539-B Preparation method of lidocaine hydrochloride impurity E 郑州原理生物科技有限公司 2023-08-11 CN disclosed
CN-114716341-A Method for preparing dimethachlor by one-pot method 上海农帆生物科技有限公司 2022-07-08 CN disclosed
WO-2022051804-A1 COMPOUNDS AND METHODS THE UNIVERSITY OF WESTERN AUSTRALIA (AU) 2022-03-17 WO disclosed
CN-113979880-A Novel method for preparing dimethachlor 上海农帆生物科技有限公司 2022-01-28 CN disclosed
CN-113979880-A Novel method for preparing dimethachlor 上海农帆生物科技有限公司 2022-01-28 CN disclosed
CN-111995539-A Preparation method of lidocaine hydrochloride impurity E 郑州原理生物科技有限公司 2020-11-27 CN disclosed
US-20120190542-A1 FUNGICIDAL MIXTURES AND THEIR USE SYNGENTA CROP PROTECTION, LLC (US) 2012-07-26 US disclosed
EP-0643687-B1 IMPROVED PROCESS FOR PREPARING N-PHENYL-N-METHOXYACETYL-DL-ALANINE METHYL ESTER DERIVATIVES NITROKEMIA IPARTELEPEK (HU) 1998-06-10 EP disclosed
US-5639905-A REACTING N-METHOXYACETYL DERIVATIVE WITH ALKALI METAL ALKOXIDE, REACTING THE METAL SALT WITH METHYL HALOPROPIONATE NITROKEMIA IPARTELEPEK (HU) 1997-06-17 US disclosed
EP-0643687-A1 IMPROVED PROCESS FOR PREPARING N-PHENYL-N-METHOXYACETYL-DL-ALANINE METHYL ESTER DERIVATIVES NITROKEMIA IPARTELEPEK (HU) 1995-03-22 EP disclosed
WO-1993020041-A1 IMPROVED PROCESS FOR PREPARING N-PHENYL-N-METHOXYACETYL-DL-ALANINE METHYL ESTER DERIVATIVES NITROKÉMIA IPARTELEPEK (HU) 1993-10-14 WO disclosed
EP-0423282-B1 PROCESS FOR PREPARING N-PHENYL-N-METHOXYACETYL-DL-ALANINE-METHYLESTER DERIVATIVES NITRO-KEMIA IPARTELEPEK (HU) 1993-08-04 EP disclosed
WO-1990012783-A1 PROCESS FOR PREPARING N-PHENYL-N-METHOXYACETYL-DL-ALANINE-METHYLESTER DERIVATIVES NITROKÉMIA IPARTELEPEK (HU) 1990-11-01 WO disclosed
EP-0019858-B1 N-OXIMINOALKYL ANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1983-06-22 EP disclosed
US-4337268-A MICROBIOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1982-06-29 US disclosed
EP-0010673-B1 SUBSTITUTED N-PROPARGYL ANILINES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1982-01-27 EP disclosed
EP-0019858-A2 N-Oximinoalkyl anilides, process for their preparation and their use as fungicides BAYER AG (DE) 1980-12-10 EP disclosed
EP-0010673-A2 Substituted N-propargyl anilines, process for their preparation and their use as fungicides BAYER AG (DE) 1980-05-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120190542-A1 FUNGICIDAL MIXTURES AND THEIR USE MLN, P2RY13, P2RX2 MEN1 1090/4885KMT2A 2660/4885CYP1A2 51/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.