Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 9/20 | 0.49 |
| ▸ | CCKBR | P32239 | 5/20 | 0.49 |
| ▸ | CCR3 | P51677 | 3/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8646939 | 0.79 | CCKAR (0.55) | CCKBR | |
| SCHEMBL8551460 | 0.78 | CCKBR (0.48) | CCKBR | |
| SCHEMBL8551465 | 0.78 | CCKBR (0.48) | CCKBR | |
| SCHEMBL8554471 | 0.77 | CCKBR (0.49) | CCKBR | |
| SCHEMBL8554771 | 0.77 | CCKBR (0.49) | CCKBR | |
| SCHEMBL9007294 | 0.75 | CCKBR (0.46) | CCKBR | |
| SCHEMBL8553128 | 0.75 | CBLB (0.56) | CBLBCCKBR | |
| SCHEMBL7808858 | 0.72 | CCKBR (0.64) | CCKBR | |
| SCHEMBL7552157 | 0.71 | CCKBR (0.75) | CCKBR | |
| SCHEMBL7552167 | 0.71 | CCKBR (0.75) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672037-B1 | 1,4-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS CCK-MODULATORS | GLAXO GROUP LTD (GB) | 1998-07-08 | — | — | EP | disclosed |
| US-5569654-A | ADMINISTERING AS ANTAGONISTS OF GASTRIN AND CHOLECYSTOKININ | GLAXO GROUP LIMITED (GB) | 1996-10-29 | — | — | US | disclosed |