Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.53 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622044 | 0.90 | POLB (0.59) | THRATHRBCA12CA1CA2 | |
| SCHEMBL8622878 | 0.89 | THRA (0.57) | THRATHRBCA12CA1CA2 | |
| SCHEMBL15329730 | 0.88 | THRA (0.69) | THRATHRBCA12CA1CA2 | |
| SCHEMBL12491077 | 0.88 | THRA (0.69) | THRATHRBCA12CA1CA2 | |
| SCHEMBL8622633 | 0.85 | ESR1 (0.69) | THRATHRBCA12CA1CA2 | |
| SCHEMBL8624821 | 0.82 | TRPV1 (0.57) | — | |
| SCHEMBL8623273 | 0.82 | TRPV1 (0.57) | — | |
| SCHEMBL8621957 | 0.82 | TRPV1 (0.57) | — | |
| SCHEMBL8624890 | 0.81 | FAAH (0.56) | S1PR1 | |
| SCHEMBL16741944 | 0.80 | THRA (0.62) | THRATHRBCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648612-B1 | Reversible heat-sensitive recording material | MITSUBISHI PAPER MILLS LTD (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5498772-A | SUBSTRATE WITH HEAT SENSITIVE LAYER AND OPTICAL RECORDING LAYER | MITSUBISHI PAPER MILLS LIMITED (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0648612-A1 | Reversible heat-sensitive recording material | MITSUBISHI PAPER MILLS, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |