Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RGS4 | P49798 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11691595 | 0.76 | SMN1; SMN2 (0.42) | TSHRLMNAALDH1A1 | |
| SCHEMBL16774865 | 0.72 | TLR8 (0.39) | TSHRLMNAHTTKDM4EALDH1A1 | |
| SCHEMBL5657269 | 0.69 | TSHR (0.36) | TSHRRGS4 | |
| SCHEMBL11381038 | 0.69 | ALDH1A1 (0.38) | TSHRALDH1A1RGS4 | |
| SCHEMBL8173050 | 0.68 | TSHR (0.35) | TSHRLMNAALDH1A1 | |
| SCHEMBL14342088 | 0.67 | HSD11B1 (0.41) | TSHRLMNAHTTALDH1A1 | |
| SCHEMBL15166513 | 0.67 | HSD11B1 (0.41) | — | |
| SCHEMBL11512011 | 0.67 | HSD11B1 (0.41) | TSHRLMNAHTTALDH1A1 | |
| SCHEMBL14557069 | 0.67 | HSD11B1 (0.41) | TSHRLMNAHTTALDH1A1 | |
| SCHEMBL9642497 | 0.67 | TLR8 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |