Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6081734 | 0.78 | ATM (0.44) | ATMNPC1RAB9A | |
| SCHEMBL4288878 | 0.78 | ATM (0.44) | ATMNPC1RAB9A | |
| SCHEMBL400031 | 0.74 | ATM (0.40) | ATMNPC1RAB9AKDM4E | |
| SCHEMBL12478396 | 0.73 | ATM (0.39) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL9769252 | 0.69 | ATM (0.45) | ATMNPC1RAB9AKDM4ECYP1A2 | |
| SCHEMBL4559941 | 0.68 | ATM (0.48) | ATMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL3535166 | 0.68 | ATM (0.48) | ATMMEN1MAPTKMT2ANPC1 | |
| SCHEMBL4620642 | 0.68 | ATM (0.48) | ATMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5259264 | 0.68 | ATM (0.48) | ATMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8424490 | 0.68 | ATM (0.48) | ATMMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716446-A | PRINTING INK; TONERS; POWDER COATING | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-02-10 | — | — | US | disclosed |
| US-5698705-A | BASED ON AMINOBENZIMIDAZOLONES | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-16 | — | — | US | disclosed |