SCHEMBL8626604

SCHEMBL8626604

C[CH]OC(=O)C(C)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 2/20 0.40
GPR55 Q9Y2T6 1/20 0.40
CA2 P00918 3/20 0.40
CA1 P00915 2/20 0.40
ALDH1A1 P00352 3/20 0.39
GAA P10253 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
POLB P06746 1/20 0.39
TYR P14679 1/20 0.39
GABBR2 O75899 2/20 0.39
GABBR1 Q9UBS5 2/20 0.39
GLRA3 O75311 1/20 0.39
GLRB P48167 1/20 0.39
NPSR1 Q6W5P4 2/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2D6 P10635 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
USP2 O75604 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5417446 0.86 HMGCR (0.40) HMGCRGPR55CA2CA1ALDH1A1
SCHEMBL29996032 0.82 HMGCR (0.37) HMGCRGPR55CA2CA1ALDH1A1
SCHEMBL490766 0.82 CA2 (0.47) HMGCRGPR55CA2CA1ALDH1A1
SCHEMBL6056065 0.81 CA2 (0.42) HMGCRGPR55CA2CA1ALDH1A1
SCHEMBL4784134 0.81 TDP1 (0.44) HMGCRGPR55CA2CA1ALDH1A1
SCHEMBL490322 0.79 HMGCR (0.44) HMGCRGPR55CA2CA1ALDH1A1
SCHEMBL29020567 0.79 CA2 (0.49) HMGCRGPR55CA2CA1ALDH1A1
SCHEMBL30559748 0.79 HMGCR (0.44) HMGCRGPR55CA2CA1ALDH1A1
SCHEMBL1894653 0.78 HMGCR (0.40) HMGCRGPR55CA2CA1ALDH1A1
SCHEMBL4776164 0.78 HMGCR (0.40) HMGCRGPR55CA2CA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5767179-A INFRARED ABSORBERS FUJI CHEMICAL INDUSTRY CO., LTD. (JP) 1998-06-16 US disclosed