Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.39 |
| ▸ | GLRB | P48167 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784134 | 0.87 | TDP1 (0.44) | HMGCRCA2CA1ALDH1A1GAA | |
| SCHEMBL4453160 | 0.84 | CA2 (0.40) | HMGCRCA2CA1ALDH1A1GAA | |
| SCHEMBL490766 | 0.82 | CA2 (0.47) | HMGCRCA2CA1ALDH1A1GAA | |
| SCHEMBL8818659 | 0.81 | ALDH1A1 (0.38) | HMGCRCA2CA1ALDH1A1GAA | |
| SCHEMBL6056065 | 0.81 | CA2 (0.42) | HMGCRCA2CA1ALDH1A1GAA | |
| SCHEMBL4359381 | 0.81 | HMGCR (0.38) | HMGCRCA2CA1ALDH1A1GAA | |
| SCHEMBL9340528 | 0.80 | CA2 (0.48) | HMGCRCA2CA1ALDH1A1GAA | |
| SCHEMBL29020567 | 0.79 | CA2 (0.49) | HMGCRCA2CA1ALDH1A1GAA | |
| SCHEMBL490322 | 0.79 | HMGCR (0.44) | HMGCRCA2CA1ALDH1A1GAA | |
| SCHEMBL30559748 | 0.79 | HMGCR (0.44) | HMGCRCA2CA1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120328541-A1 | Anti-radical agents | BASCHONG WERNER (CH) | 2012-12-27 | — | — | US | disclosed |
| US-8216596-B2 | 4-Hydroxy-1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethylpiperidine, citric acid and a body care product; hindered amine salt compounds provide outstanding protection against light-induced fading | BASF SE (DE) | 2012-07-10 | — | — | US | disclosed |
| US-20120164162-A1 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BASF SE (DE) | 2012-06-28 | — | — | US | disclosed |
| US-20120121524-A1 | PHOTO-STABLE COSMETIC OR DERMATOLOGICAL COMPOSITIONS | MUELLER STEFAN (DE) | 2012-05-17 | — | — | US | disclosed |
| US-8148318-B2 | Home or fabric care compositions comprising certain dye-polymer complexes | BASF SE (DE) | 2012-04-03 | — | — | US | disclosed |
| US-8119107-B2 | Photo-stable cosmetic or dermatological compositions | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20100143272-A1 | Photo-stable cosmetic or dermatological compositions | CIBA SPECIALTY CHEMICALS CORPORATION | 2010-06-10 | — | — | US | disclosed |
| US-7700078-B2 | Stabilization of body-care and household products | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-04-20 | — | — | US | disclosed |
| US-7632795-B2 | Stabilized body care products, household products, textiles and fabrics | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-12-15 | — | — | US | disclosed |
| US-7618618-B2 | Stabilized body care products, household products, textiles and fabrics | CIBA SPECIALTY CHEMICALS CORP. (US) | 2009-11-17 | — | — | US | disclosed |
| US-20090060849-A1 | Personal care compositions comprising certain dye-polymer complexes | BASF SE (DE) | 2009-03-05 | — | — | US | disclosed |
| US-20090062171-A1 | Home or fabric care compositions comprising certain dye-polymer complexes | BASF SE (DE) | 2009-03-05 | — | — | US | disclosed |
| US-20080305055-A1 | Anti-Radical Agents | CIBA CORPORATION | 2008-12-11 | — | — | US | disclosed |
| US-20080279794-A1 | Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin | BASCHONG WERNER | 2008-11-13 | — | — | US | disclosed |
| US-20080260667-A1 | Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin | BASCHONG WERNER | 2008-10-23 | — | — | US | disclosed |
| US-20080253981-A1 | Stabilized body care products, household products, textiles and fabrics | LUPIA JOSEPH A | 2008-10-16 | — | — | US | disclosed |
| US-7425320-B2 | Use of guaiol for treating the skin | CIBA SPECIALTY CHEMICALS CORP (US) | 2008-09-16 | — | — | US | disclosed |
| US-7410940-B2 | Antioxidants for the stabilization of surfactant formulations | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-08-12 | — | — | US | disclosed |
| US-20080108540-A1 | Antioxidants for the stabilization of formulations comprising surfactants | HUEGLIN DIETMAR | 2008-05-08 | — | — | US | disclosed |
| US-20080009550-A1 | Stabilized body care products, household products, textiles and fabrics | LUPIA JOSEPH A | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120121524-A1 | PHOTO-STABLE COSMETIC OR DERMATOLOGICAL COMPOSITIONS | NISCH, CUTA, MITF | HMGCR 530/4885CA2 2937/4885CA1 4458/4885 |
| US-20120328541-A1 | Anti-radical agents | NOS3, GSTO1, TXN2 | HMGCR 1280/4885CA2 454/4885CA1 1327/4885 |
| US-20080253981-A1 | Stabilized body care products, household products, textiles and fabrics | DSC1, CUTA, DSG1 | HMGCR 4363/4885CA2 3470/4885CA1 3166/4885 |
| US-20090060849-A1 | Personal care compositions comprising certain dye-polymer complexes | ERCC5, XRCC5, ERCC1 | HMGCR 1022/4885CA2 2649/4885CA1 3491/4885 |
| US-20080305055-A1 | Anti-Radical Agents | NOS3, GSTO1, PTGS1 | HMGCR 1491/4885CA2 356/4885CA1 1070/4885 |
| US-20120164162-A1 | METHODS IN CELL CULTURES, AND RELATED INVENTIONS, EMPLOYING CERTAIN ADDITIVES | BBOX1, NEFM, NQO1 | HMGCR 1140/4885CA2 633/4885CA1 2395/4885 |
| US-20100143272-A1 | Photo-stable cosmetic or dermatological compositions | DBF4, CUTA, ARSA | HMGCR 3103/4885CA2 1825/4885CA1 2514/4885 |
| US-20080260667-A1 | Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin | MC1R, TYR, MC3R | HMGCR 639/4885CA2 1991/4885CA1 4302/4885 |
| US-20080279794-A1 | Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin | MC1R, TYR, MC3R | HMGCR 639/4885CA2 1991/4885CA1 4302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.